Newsletter Archive
RodPorterConsultancy Newsletter Oct 2014 vol 5 no_5 Q2 Regulatory approvals, Patent cliff 2013, who holds what – NME’s, Oncology reasons for failure, PAINful screening, Intrinsic clearance not PPB, Ionisation state and drug discovery, HDAC imaging, Screening strategies, P450 design out, Thiophenes and toxicity, Enzyme mediated chlorination, Photoredox, Useful illustrations, LINCS
RodPorterConsultancy Newsletter July 2014 vol 5 no_4 Big Beasts of the Future, Academy of Sciences report, peptide therapeutics, In vitro toxicology, Aromaticity descriptors, Finding binding sites, Transporters, Disordered proteins, SF5 – good bad or ugly, CNS penetrant ALK inhibitors, Translating P-gp substrates, Synthesis of ArCF2X
RodPorterConsultancy Newsletter June 2014 vol 5 no_3 Next generation, Drug approvals, From boom to bust, Megamergers, early response genes, Sex equality, Metabolite exposure, Validity of efficiency metrics part II, pi-stacking, QED scores, predicting clearance, transport v. passive permeability, long acting injectables, PPI reviews, Don’t forget chemistry, CH activation , nickel Cell Press, Lists, Recon 2.
RodPorterConsultancy Newsletter Aprl 2014 vol 5 no 2 Content of the April 2014 vol 5 no 2 Rod Porter Consultancy Newsletter: Complete response letters, Compounds approvedby company, Models, Sydney Brenner, ProteomeXchange, Once weekly dosing, Kinases, Peptides, Unbound drug fraction, Intramolecular H-bonds, Chromones – drugs, Directed meta-substitution, Pd CH-activation, ToxTree, Nature advances reviews
Rod Porter Consultancy Newsletter March 2014 vol 5 no_1 (1): IPO’s, 2014 pipeline value, Detecting Concussion, ADME SARfari, EPO synthesis, Developability – toxcast, hepatotox and AO, Rings in drugs, CNS delivery, P-gp, ligand efficiency (again), druggable PPI’s, (Hetero)Arylmethylketone synthesis
Rod Porter Consultancy Newsletter Dec 2013 vol 4 no 6
Rod Porter Consultancy News Letter October 2013 vol 4 no_5
Rod Porter Consultancy Newsletter September 2013 vol 4 4
RodPorter Consultancy Newsletter June 2013, vol 4, no 3
Rod Porter Consultancy Newsletter April 2013 vol 4 no 2
Rod Porter Consultancy Newsletter Feb 2013 vol 4_1
Rod Porter Consultancy Newsletter Dec 2012
November 2012, vol 3, no. 5
September 2012 vol 3 no 4
July 2012, vol 3, no. 3
May 2012, vol 3, no. 2
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Rod